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CRISPR Base Editors Are Often Off Base with RNA

CRISPR base editors are supposed to be parsimonious. They avoid inflicting anything so extreme as a double-strand break, and they confine their genomic activities to single-nucleotide changes—reasonably on-target changes. Yet CRISPR base editors can indulge in wanton behavior, report scientists based at Massachusetts…

A Breath of Fresh CRISPR

Genome editing materials can’t just breeze into cells. Or can they? Even cells so well defended as lung and airway cells may admit wisps of genome editing proteins such as CRISPR-associated nucleases. All that’s needed is an inspired delivery method. One possibility is the aerosolization of amphiphilic peptides.…

single-Cell RNA Seq Creates Human Liver Cell Atlas

Liver diseases such as fatty liver disease, liver cancer, and hepatitis—to name a few—are a leading cause of death worldwide. Despite the immense importance of the liver for human health, a rising incidence of liver diseases, and limited treatment options, the diversity of cell types in the liver and their various…

107 Nobel Laureates Sign Letter Blasting Greenpeace Over GMOs

While Greenpeace and other organizations oppose genetically engineered food, more than 100 Nobel laureates are taking a stand on the side of GMOs. More than 100 Nobel laureates have signed a letter urging Greenpeace to end its opposition to genetically modified organisms (GMOs).

WHO/FAO: glyphosate is safe

Genetically modified products are safe and clean without the use of dangerous chemical pesticides, also supply human health, the environment will be maintained. Safety of biotechnology has been approved repeatedly by the World Health Organization (WHO), the World Trade Organization (WTO), the United Nations Food and…

Nobel Prize in Chemistry Awarded to DNA Repair Researchers

Recipients of the Nobel Prize in Chemistry were announced today acknowledging three scientists that made fundamental contributions to the study of how cells repair DNA and maintain genomic integrity. Each day our DNA is damaged by UV radiation, free radicals, and other carcinogenic substances.

New Method to Regulate Stem Cell Differentiation

Scientists at the University of Helsinki in Finland say they have developed a new method that enables the activation of genes in a cell without changing the genome. Applications of the method include directing the differentiation of stem cells.

USDA Approves Simplots GM Potato

The U.S. Department of Agriculture (USDA) has approved InnateTM potato (designated as Russet Burbank event W8), which has been genetically engineered for late blight resistance, low acrylamide potential, reduced black spot bruising, and lowered reducing sugars. Late ...

Gene Stacking Provides Better Resistance in Potato against Late Blight

Scientists from Ghent University, VIB, Institute for Agricultural and Fisheries Research (ILVO) and partners released the results of their GM potato field study in the journal Crop Protection. The field trials of GM potatoes were conducted in Belgium and Netherlands to investigate the efficacy ...